Phytoestrogens effects on er breast cancers

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Category: Army
Added: 05.02.2021
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US Pharm. Phytoestrogens are trace biochemicals produced by plants that act like estrogens in animal cells and bodies. A number of epidemiological studies have reported a connection between high dietary intake of phytoestrogens and lower rates of certain cancers, cardiovascular problems, and menopausal symptoms. Although still inconclusive, scientific evidence is accumulating to suggest that phytoestrogens may have a role in preventing chronic disease. Phytoestrogens mainly fall into the class of flavonoids: the most potent in this class are coumestans and isoflavones genistein and daidzein.
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Breast cancer - Wikipedia

Plant based natural products have been proposed as alternatives to the use of hormones for the treatment of menopausal symptoms, which has been associated with an increased risk of breast cancer and coronary artery disease. Specific herbal compounds such as Thai Kudzu root Pueraria mirifica have shown beneficial effects in the treatment of peri-menopausal symptoms and menopausal-related osteoporosis when used as an adjunct or as a single medicine. Clinically, these compounds require careful dosing and are associated with variable times to efficacy. No known drug interactions exist, although research on the effects of phytoestrogens is limited.
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Breast cancer

Phytoestrogens are plant hormones chemically similar to the estrogens found in humans. An example of a phytoestrogen is soy. Phytoestrogens treat a variety of health conditions and affect breast tissue.
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Phytoestrogens derived from plants exert estrogenic as well as antiestrogenic effects and multiple actions within breast cancer cells. Chemopreventive properties of phytoestrogens have emerged from epidemiological observations. In recent clinical research studies, phytoestrogens are safe and may even protect against breast cancer. In this brief review, the molecular mechanisms of phytoestrogens on regulation of cell cycle, apoptosis, estrogen receptors, cell signaling pathways, and epigenetic modulations in relation to breast cancer are discussed.
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